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选择性神经切断联合胫骨横向骨搬移术治疗下肢血栓闭塞性脉管炎疗效分析
Analysis of therapeutic efficacy of selective neurotomy combined with tibial transverse transport in the treatment of thromboangiitis obliterans of the lower extremities procedure
投稿时间:2024-12-09  
DOI:10.3969/j.issn.1672-5972.2025.06.011
中文关键词:  下肢血栓闭塞性脉管炎  胫骨横向骨搬移术  选择性神经切断术
英文关键词:Thromboangiitis obliterans of the lower extremities  Tibial transverse bone transport  Selective neurotomy operation
基金项目:
作者单位邮编
石守印* 新疆维吾尔自治区人民医院骨科中心新疆 乌鲁木齐830001 830001
周敏* 新疆生产建设兵团医院神经外科新疆 乌鲁木齐830001 830001
海拉提·巴合提 新疆维吾尔自治区人民医院骨科中心新疆 乌鲁木齐830001 830001
李祖涛 新疆维吾尔自治区人民医院骨科中心新疆 乌鲁木齐830001 830001
赵清斌 新疆维吾尔自治区人民医院骨科中心新疆 乌鲁木齐830001 830001
殷剑 新疆维吾尔自治区人民医院骨科中心新疆 乌鲁木齐830001 830001
孙俊刚 新疆维吾尔自治区人民医院骨科中心新疆 乌鲁木齐830001 830001
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中文摘要:
      目的 总结我院采用选择性神经切断联合胫骨横向骨搬移术(tibial transverse transport, TTT)治疗下肢血栓闭塞性脉管炎(thromboangiitis obliterans, TAO)的临床疗效。方法 回顾性分析新疆维吾尔自治区人民医院自2017年10月至2023年10月期间,采用选择性神经切断联合TTT技术治疗的60例TAO患者资料。首先,对所有患者的足部溃疡创面实施扩大清创术,彻底清除坏死及病变组织。依据术前体格检查和术中探查结果,精确定位疼痛敏感区域所对应的感觉神经,并实施彻底的神经松解。对于存在显著脱髓鞘病变的神经,术中给予部分选择性神经切断。随后,行TTT手术治疗。通过随访,对比患者手术前后的足背皮温、经皮氧分压(TcPO₂)、踝肱指数(ABI)、间歇性跛行距离、疼痛视觉模拟评分(VAS)及创面愈合情况,综合评估治疗效果。结果 本组患者均获得随访,随访时间6~12个月,平均(8.0±2.4)个月。60例患者术后慢性溃疡创面一期愈合57例(95%),延迟愈合3例(5%),钉道感染2例(3.3%),围手术期肢体静息性疼痛或间歇性跛行完全缓解,无溃疡复发、骨折等并发症发生。术后足部皮温、经皮氧分压(TcPO₂)、ABI、间歇性跛行距离、VAS评分较术前均有明显改善,差异有统计学意义(P<0.05)。结论 选择性神经切断联合TTT治疗TAO,创伤小、临床效果显著,尤其是对血管闭塞引起的肢体末端缺血性疼痛效果较好,在选择合适手术适应证的前提下,值得临床推广应用。
英文摘要:
      Objective To summarize the clinical efficacy of selective neurotomy combined with tibial transverse transport (TTT) technique in the treatment of thromboangiitis obliterans (TAO) of the lower extremities in our hospital.Methods A retrospective analysis of the medical records of 60 TAO patients who underwent selective neurotomy combined with the TTT technique at the People's Hospital of the Xinjiang Uyghur Autonomous Region between October 2017 and October 2023 was conducted. Firstly, extensive debridement was performed on the foot ulcer wounds of all patients to thoroughly remove necrotic and pathological tissues. Based on preoperative physical examinations and intraoperative exploration results, the sensory nerves corresponding to pain-sensitive areas were accurately located and underwent thorough neurolysis. For nerves with significant demyelinating lesions, partial selective neurotomy was performed intraoperatively. Subsequently, TTT surgery was conducted. Follow-up visits were arranged to compare patients' dorsal foot skin temperature, transcutaneous oxygen pressure (TcPO2), ankle-brachial index (ABI), intermittent claudication distance, visual analog scale (VAS) for pain, and wound healing status before and after surgery, comprehensively assessing the therapeutic effects.Results All patients in this group were followed up for 6-12 months, with an average of (8.0±2.4) months. Of the 60 patients, 57 patients (95%) experienced primary healing of chronic ulcer wounds postoperatively, 3 patients (5%) had delayed healing and 2 patients (3.3%) had pin tract infections. Rest pain or intermittent claudication in the extremities was completely relieved during the perioperative period, with no complications such as ulcer recurrence or fractures occurring. Postoperative dorsal foot skin temperature, TcPO2, ABI, intermittent claudication distance, and VAS scores were significantly improved compared to preoperative levels, with statistically significant differences (P<0.05).Conclusion Selective neurotomy combined with TTT in the treatment of TAO is minimally invasive and demonstrates significant clinical efficacy, especially for ischemic pain in the extremities caused by vascular occlusion. Provided that appropriate surgical indications are selected, this method is worthy of clinical promotion and application.
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