| Existing bone defect repair materials do not meet clinical needs in terms of mechanical properties, degradation rates and bioactivity. There is therefore an urgent need to develop new bone repair materials. Akermanite (Akt), a representative calcium-magnesium silicate-based bioceramic, has emerged as a research hotspot in bone tissue engineering owing to its compressive strength (approximately 176 MPa) comparable to human bone, moderate degradation rate, and sustained release of bioactive ions (Mg²⁺, Ca²⁺, Si⁴⁺). This article systematically reviews recent advances in Akt properties, preparation, and composite scaffolds, with a focus on summarizing the preparation and application research of Akt containing composite materials, surface coatings, and doped Akt, as well as the performance characteristics of different materials. Although these materials have their own characteristics, the clinical translation of Akt-based materials still requires resolution of critical issues, including long-term biosafety, dynamic adaptability, and scaled-up fabrication. |
