Objective To investigate the clinical effect of the application of simple Pelnac skin grafting and Pelnac combined with autologous skin grafting for the treatment of fresh fingertip defects. Methods Between Jan 2013 and Dec 2015, 61 patients with fingertip defects were randomly divided into experimental group and control group according to the patients’ admission time odd numbers and even numbers, patients in the experimental group were treated with skin grafting of Pelnac, and the control group was treated with Pelnac combined with autologous thin skin grafting for the treatment of fingertip defects. All patients were given effective treatment, regular dressing and scheduled follow-up. Results In scar formation, postoperative infection, secondary operation , pain and warm sonse , there were no significance diffevence between the two groups(P>0.05). While, comparing the color, elasticity, length of hospital stay and cost of treatment, there was statistical difference in the Pelnac group than in the autologous skin group(P<0.05), the Pelnac group was superior than the autologous skin group, however, the healing time of the autologous skin group was shorter than that of the Pelnac group(P<0.05). Conclusion In terms of the overall therapeutic effect, the two groups were similar. The use of Pelnac in clinical application is simpler, without re-operation injuries, with shorter length of hospital stay and low treatment cost, and the appearance was ample and flexible. Pelnac in the treatment of fingertip defect is effective and safe, and easy to popularize in the grass-roots level hospital. |