Objective To compare the clinical outcomes of unipedicular percutaneous vertebroplasty (PVP) with that of bipedicular PVP in the treatment of osteoporotic vertebral compression fractures. Methods Seventy eight patients with single osteoporotic vertebral compression fractures were treated by PVP from January 2016 to May 2018. They were divided into two groups according to their surgical approach. There were 33 cases in the unilateral group, including 6 males and 27 females, aged from 56 to 100 years, with an average age of (74.2±9.6) years; and there were 45 cases in the bilateral group, including 6 males and 39 females, aged from 57 to 94 years, with an average age of (75.0±8.3) years. Clinical outcomes were assessed by using visual analogue scale (VAS), operation time, injection volume of bone cement, rate of cement leakage, compression ratio and kyphotic Cobb angle of fracture vertebral before and after surgery, restoration ratio of the vertebral height and correction ratio of the kyphotic Cobb angle after surgery. Results The postoperative VAS were significantly lower than preoperative VAS (P<0.05) in both groups, but there was no significant difference between the two groups in analgesic effect after PVP (P>0.05). In the unilateral group, the average operative time (56.9±29.7) min and the average amount of bone cement injection (2.6±1.0) mL were significantly less than that of the bilateral group, (71.1±25.7) min and (4.1±1.1) mL (P<0.05). No significant difference was observed between the unilateral group (18.2%, 6/33) and the bilateral group (15.6%, 7/45) at the rate of bone cement leakage (P>0.05). The compression ratio and kyphotic Cobb angle of fracture vertebral were statistically improved in both two groups after surgery (P<0.05); furthermore, there was no significant difference between the two groups in the restoration ratio of the vertebral height and correction ratio of the kyphotic Cobb angle after surgery (P>0.05). Conclusion The short-term clinical effects of unipedicular PVP are as same as that of bipedicular PVP in the treatment of osteoporotic vertebral compression fractures, and the unipedicular PVP had shorter operation time and less trauma. |