Objective To observe and analyze the clinical effect of high viscosity bone cement combined with bone expander system and percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fracture (OVCF). Methods A total of 224 patients with OVCF admitted to our hospital from October 2014 to February 2017 were enrolled. They were divided into two groups by random double-blind method. A total of 112 patients in the observation group were treated with high viscosity bone cement combined with bone expander system for vertebroplasty. The other 112 patients in the control group were treated with high viscosity bone cement PKP. The operation time, intraoperative blood loss, injection volume of bone cement, incidence of bone cement leakage and diffusion coefficient of bone cement, and changes of Cobb angle, vertebral height and visual analogue scale (VAS) score before operation, at 1d and 1 year after operation, and postoperative satisfaction were compared between the two groups. Results The operation time, intraoperative blood loss and injection volume of bone cement in the observation group were significantly fewer than those in the control group (P<0.05). The incidence of bone cement leakage in the observation group was significantly lower than that in the control group (P<0.05). There was no significant difference in the diffusion coefficient of bone cement between the two groups (P>0.05). There was no significant difference in Cobb angle, or anterior height of the injured vertebra between the two groups at 1 d and 1 year after operation (P>0.05). There was no significant difference in VAS score between the two groups at 1 d and 1 year after operation (P>0.05). There was no significant difference in postoperative satisfaction between the two groups (P>0.05). Conclusion The effect of high viscosity bone cement combined with bone expander system is similar to that of high viscosity bone cement PKP in the treatment of patients with OVCF. However, the combined treatment can effectively shorten the operation time, reduce the bleeding volume, and reduce the rate of bone cement leakage. |