| Objective A systematic review of the efficacy of opening wedge high tibial osteotomy (OWHTO) with intraoperative bone graft versus no bone graft by meta-analysis was conducted. Methods Through computer search of PubMed, Cochrane Library, Embase, CNKI, Wanfang database from the establishment of the database to April 2021, all clinical comparative studies of with and without bone graft in open wedge high tibial osteotomy were searched. After literature screening, quality evaluation and data extraction were carried out according to the inclusion criteria and exclusion criteria, and the Revman 5.4 software was used to conduct a Meta analysis of each evaluation index. Results A total of 10 articles were included, including 581 knee joint cases, including 279 cases with bone grafts and 302 cases without bone grafts. Meta-analysis results showed that: Compared with non-grafted bone, the bone healing time [MD=-0.2, 95%CI(-0.26, -0.14), P<0.001], postoperative FTA [MD=0.7, 95%CI(0.23, 1.17), P=0.004] had a statistical differences, but the rate of bone healing at 3 months postoperatively, postoperative correction loss angle, postoperative KSSK, postoperative KSSF, postoperative Lysholm Knee Score, postoperative IKDC Score, and postoperative complications had no statistical difference. Conclusion Both groups of patients achieved good postoperative function and curative effect. The bone healing in the open wedge-shaped high tibial osteotomy and bone grafting group was faster, but there was no difference in the bone healing rate 3 months after operation. Therefore, if the distraction height after osteotomy was small, no bone grafting could be considered. |
