Metal-based 3D(three-dimensional) printed scaffolds are an important modality used to treat bone defects. With the development of technology, metal-based 3D printed scaffolds have started to evolve various functions in recent years, mainly including: antibacterial, drug delivery and drug-controlled release, and induced osteogenesis. In order to achieve different functions of metal scaffolds, specific building processes and modalities are required, such as improved topology, micro-arc oxidation, nano-modification, surface coating, etc. This paper presents a review of the current research progress in the construction and functionalization of metal-based 3D printed scaffolds in orthopedics. |