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采用“双侧垂直错位穿刺法”与“双侧水平裂隙穿刺法”行经皮椎体成形术在治疗Ⅰ期Kümmell病的疗效对比
Comparison of "noncoplanar bipedicular puncture method" and "coplanar bipedicular puncture method" for vertebroplasty in the treatment of stage I Kümmell disease
投稿时间:2022-05-05  修订日期:2022-06-24
DOI:10.3969/j.issn.1672-5972.2022.06.007
中文关键词:  经皮椎体成形术  Kümmell病  骨水泥  双侧垂直错位穿刺法
英文关键词:Percutaneous vertebroplasty  Kümmell disease  Bone cement  Noncoplanar bipedicular puncture
基金项目:
作者单位E-mail
郝国兵* 中国人民解放军火箭军特色医学中心骨科北京100088 hguobing@163.com 
朱泽兴 中国人民解放军火箭军特色医学中心骨科北京100088  
刘昆 中国人民解放军火箭军特色医学中心骨科北京100088  
杨勇 中国人民解放军火箭军特色医学中心骨科北京100088  
张楠 中国人民解放军火箭军特色医学中心骨科北京100088  
闫双宝 中国人民解放军火箭军特色医学中心骨科北京100088  
陈福文 中国人民解放军火箭军特色医学中心骨科北京100088  
乔林* 中国人民解放军火箭军特色医学中心骨科北京100088 18910883457@163.com 
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中文摘要:
      目的 探究采用“双侧垂直错位穿刺法”与“双侧水平裂隙穿刺法”行经皮椎体成形术(PVP)在治疗I期Kümmell病中的疗效对比。方法 回顾性分析2014年1月至2021年1月在中国人民解放军火箭军特色医学中心接受PVP治疗的I期Kümmell病患者53例,其中采取“双侧垂直错位穿刺法”治疗25例(A组),采取“双侧水平裂隙穿刺法”治疗28例(B组)。比较两组的手术时间、骨水泥注入量、骨水泥渗漏率、骨水泥分布及并发症情况,并记录术前与术后1 d、1个月、3个月、6个月视觉评分量表(VAS)和Oswestry功能障碍指数(ODI),通过X线或CT检查测量并记录术前、术后伤椎前缘与中线高度和Cobb角,并观察骨水泥松动或移位及伤椎再骨折发生情况,末次随访采用改良MacNab标准评估手术的优良率。结果 两组患者均顺利完成手术,均获定期随访。A组较B组手术时间相当(P>0.05),骨水泥注入量更多(P<0.05);A组术中2例出现骨水泥渗漏,渗入椎间盘1例、椎体前侧1例,无临床症状;B组术中9例出现骨水泥渗漏,渗入椎间盘6例、椎体前侧3例,无临床症状;A组术中骨水泥渗漏率较低(P<0.05),术后椎体裂隙及骨折线周围骨水泥分布更广泛(P<0.05);两组术中均无脊髓、椎前大血管损伤,无肺栓塞等并发症发生。与术前比较,两组患者术后1 d、1个月、3个月、6个月VAS、ODI显著降低(P<0.05);A组与B组比较,术前、术后VAS、ODI在两组间差异无统计学意义(P>0.05);与术前比较,两组患者术后1 d、1个月、3个月、6个月伤椎前缘与中线高度显著增加(P<0.05),Cobb角测量值显著降低(P<0.05);A组与B组比较,术后1 d、1个月、3个月、6个月伤椎前缘与中线高度变化、伤椎Cobb角变化差异无统计学意义(P>0.05);末次随访时两组患者均无骨水泥松动或移位及伤椎再骨折情况发生,采用改良MacNab标准评定临床疗效:A组优23例、良2例,B组优19例、良9例,A组优秀率高于B组(P<0.05)。结论 治疗Ⅰ型Kümmell病时,与“双侧水平裂隙穿刺法”经皮椎体成形术相比,“双侧垂直错位穿刺法”经皮椎体成形术术中的骨水泥渗漏率更低,骨水泥分布更广泛,术后早期治疗效果相当,中期效果更确切。
英文摘要:
      Objective To compare the efficacy of percutaneous vertebroplasty (PVP) with "noncoplanar bipedicular puncture method" and "coplanar bipedicular puncture method" in the treatment of stage I Kümmell disease.Methods From January 2014 to January 2021, 53 patients with stage I Kümmell disease who received PVP treatment in PLA Rocket Force Characteristic Medical Center were reviewed, including 25 cases treated with "noncoplanar bipedicular puncture method" (group A) and 28 cases treated with "coplanar bipedicular puncture method" (group B). The operative duration, the amount of bone cement injected, intraoperative cement leakage rate, bone cement distribution and complications of the two groups were compared, and the visual score scale (VAS) and Oswestry dysfunction index (ODI) were recorded before operation and 1 d, 1 month, 3 months and 6 months after operation. The anterior and midline height and Cobb angle of the injured vertebral body before and after operation were measured and recorded by X-ray or CT, and the loosening or displacement of bone cement and the occurrence of refracture of injured vertebra were observed. At the last follow-up, the improved MacNab standard was used to evaluate the excellent and good rate of the operation.Results The operation was successfully completed in both groups, all patients received regular follow-up. The operative duration in group A was similar to group B (P>0.05), and the amount of bone cement injection in group A was more than group B (P<0.05). In group A, bone cement leakage occurred in 2 cases, infiltration into intervertebral disc in 1 case and anterior vertebral body in 1 case, without neurological symptom. In group B, 9 cases had bone cement leakage, 6 cases penetrated into intervertebral disc and 3 cases in front of vertebral body, without neurological symptom. The intraoperative bone cement leakage rate in group A was smaller than that in group B, and the bone cement around the vertebral fracture line in group A was more widely distributed after operation (P<0.05). There were no spinal cord and prevertebral vascular injury, pulmonary embolism and other complications in both groups. Compared with preoperation, VAS and ODI in the two groups both decreased significantly 1 d, 1 month, 3 months and 6 months after operation (P<0.05); there was no significant difference in VAS and ODI between group A and group B (P>0.05). Compared with preoperation, the height of anterior and midline of injured vertebrae increased significantly 1 d, 1 month, 3 months and 6 months after operation (P<0.05), and the measured value of Cobb angle decreased significantly (P<0.05). Compared with group B, there were no significant changes in the height of anterior and midline of injured vertebra and Cobb angle of injured vertebra 1 d, 1 month, 3 months and 6 months after operation (P>0.05). At the last follow-up, there was no loosening or displacement of bone cement and refracture of injured vertebrae in both groups. The clinical efficacy was evaluated by the modified MacNab standard: 23 cases in group A were excellent and 2 cases were good, 19 cases in group B were excellent and 9 cases were good. The excellence rate of group A was higher than that of group B (P<0.05).Conclusion In the treatment of stage I Kümmell disease, percutaneous vertebroplasty with "noncoplanar bipedicular puncture method" has lower leakage rate and wider distribution of bone cement than percutaneous vertebroplasty with "coplanar bipedicular puncture method". The early treatment effect is equivalent and the later effect is more accurate.
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